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> Panax.Ext - Press Release Articles ( based on active ingredient curcumin in Panax.Ext ) |
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UCLA / VA Study Finds Chemical Found in Curry May Help Immune System Clear Amyloid Plaques Found in Alzheimer’s Disease UCLA / VA researchers found that curcumin - a chemical found in curry and turmeric - may help the immune system clear the brain of amyloid beta, which form the plaques found in Alzheimer's disease. Published in the Oct. 9 issue of the Journal of Alzheimer's Disease, the early laboratory findings may lead to a new approach in treating Alzheimer's disease by enhancing the natural function of the immune system using curcumin, known for its anti-inflammatory and anti-oxidant properties... » read the whole article |
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Curry Spice May Fight Alzheimer's Disease Early Studies Show Curry Reduces Plaque Buildup in Brain Linked to Disease The compound that gives the popular Indian spice curry its mustard yellow color may ward off Alzheimer's disease. Researchers at UCLA have shown that the curry pigment curcumin slows the formation of, and even destroys, accumulated plaque deposits in mouse brains. Brain plaque, sticky clumps of beta-amyloid protein, are believed to play a key role in the development of Alzheimer's dementia. Curry is a dietary staple in India, a country where the rate of Alzheimer's disease is among the world's lowest. For centuries, doctors practicing traditional Indian medicine have safely prescribed curcumin in extract form for a variety of illnesses and ailments. Researchers say curry's powerful antioxidant and anti-inflammatory properties make it a very attractive possibility for treating diseases such as Alzheimer's, cancer, and heart disease... ... For this study, scientists raised two groups of mice, one that was fed a diet high in curcumin and the other a regular diet. Previous research in mice has shown that daily curcumin lowers plaque deposits in the brain... » read the whole article |
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A spicy ingredient of many curries may be an effective treatment for Alzheimer's disease, say researchers. A team from the University of California at Los Angeles believes that turmeric may play a role in slowing down the progression of the neurodegenerative disease. The finding may help to explain why rates of Alzheimer's are much lower among the elderly in India than in their Western peers. Previous studies have found that Alzheimer's affects just 1% of people over the age of 65 living in some Indian villages... ...Turmeric is found in everything from mild Kormas to the hottest Vindaloos. The crucial chemical is curcumin, a compound found in the spice. Alzheimer's is linked to the build up of knots in the brain called amyloid plaques... » read the whole article |
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Spice Up Your Brain Preserve brain function with spicy foods. Here’s a tasty thought. Kicking your food up a notch with spices could preserve brain function and keep your brain sharp and strong as you age. Take turmeric, a spice that lends curries their yellow tint. It can curb mental decline and even slow the effects of neurodegenerative diseases such as Alzheimer’s. Researchers find it can effectively fight oxidation, the process behind a variety of bodily diseases. In the brain, oxidation trips up communication between brain cells, impairing general mental functions such as memory... » read the whole article |
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MORE ARTICLES |
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Life Extension.com » Can Curcumin Prevent Alzheimer's Disease? |
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Curcumin has long been prized in traditional Chinese and Indian medicine as a natural remedy for a variety of ailments. In modern research laboratories, curcumin’s ability to scavenge free radicals and suppress inflammatory cytokines has impressed scientists who are seeking ways to prevent and treat Alzheimer’s disease and other neurodegenerative disorders... » read the whole article |
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U.S. Department of Health and Human Services » Curry Ingredient May Help Fight Alzheimer's |
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Curcumin, a component of curry and turmeric, seems to help the immune system get rid of amyloid beta -- the protein that builds up to form damaging plaques in the brains of Alzheimer's patients. The findings build on previous research linking curry consumption to reduced Alzheimer's risk, including one study that found that only 1 percent of elderly Indians developed the disease -- a quarter of the rate seen in the United States. Now, preliminary findings from the University of California, Los Angeles, suggest that curcumin comes to the aid of immune system cells called macrophages to clear away amyloid beta. "We know that macrophages aren't working properly in Alzheimer's patients, since they seem to be defective in cleaning amyloid-beta from brain slices", explained lead researcher Dr. Milan Fiala, a researcher with the David Geffen School of Medicine at UCLA and the VA Greater Los Angeles Health Care System. "We have found that curcumin can help some macrophages to function properly in a test tube," Fiala said. He said more work is needed to see if the spice works similarly in the human brain, however. Curcumin is already known for its anti-inflammatory and antioxidant properties. Earlier research by another UCLA team found that curcumin-fed mice with Alzheimer's plaques experienced a decrease in inflammation and reduced plaque formation... |
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Heatlh and Age.com » Can Curry Protect Against Alzheimer's? |
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Summary: Blood macrophages from Alzheimer patients have lost their ability to take up amyloid-beta protein, which is commonly found in the brain of such patients. Addition of curcuminoids (a curcumin complex derived from tumeric and curry) restores the ability of the macrophages to remove amyloid-beta. Introduction: Elderly people in India have a low rate of Alzheimer's disease - about 1%, compared with roughly 4% for similarly aged persons in the USA. This fact inspired researchers in Singapore to study the possible association between eating curry and the frequency of Alzheimer's.1 Curry is often spiced with turmeric, which contains curcumin, a potent anti-inflammatory and anti-oxidant, so it's a logical 'target' for such studies... » read the whole article |
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Pro Health - Alzheimer Support.com » Research: Can Curcumin Help Prevent Alzheimer's Disease? |
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Curcumin, the yellow pigment in curry spice, is to be investigated for its potential in prevention of Alzheimer’s disease after tests on mice found it to be more effective than drugs currently being investigated for treatment. A dietary staple of India, where Alzheimer's disease rates are reportedly among the world's lowest, curcumin appears to block and break up brain plaques that cause the disease. The spice has also been found to correct the cystic fibrosis defect in mice, prevent the onset of alcoholic liver disease and may slow down the blood cancer multiple myeloma as well as multiple sclerosis. Reporting in the 7 December online edition of the Journal of Biological Chemistry, researchers from the University of California Los Angeles also revealed that curcumin is more effective in inhibiting formation of the protein fragments than many other drugs being tested as Alzheimer's treatments... » read the whole article |
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Bay Biotech.net » Curcumin finds a new role in combating Alzheimer's disease |
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Curcuma longa is a ginger-like plant that grows in tropical regions. The roots contain a bright yellow substance (turmeric) that contains curcumin and other curcuminoids. Turmeric has been used in Ayurvedic and Chinese medicine for centuries. But it's only within the past few years that the extraordinary actions of curcumin against cancer have been scientifically documented. Alzheimer's disease (AD) involves amyloid (Abeta) accumulation, oxidative damage and inflammation, and risk is reduced with increased antioxidant and anti-inflammatory consumption... » read the whole article |
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Hungtington's Outreach Program for Education at Stanford » How this Alzheimer's Research May Affect Huntington's Disease |
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Although research to confirm such a notion is just now getting underway, the results of the Alzheimer's study suggest that curcumin might well be helpful in combating other neurodegenerative diseases like HD. Despite the differences in the fundamental "cause" of each disease - HD is believed to be a purely genetic disorder, while AD is believed to have both genetic and environmental components - the damage to nerve cells in each disorder is strikingly similar. Thus, because curcumin combats the phenomena that contribute to neurodegeneration in AD, it is fair to suggest that the substance may possibly be capable of combating similar phenomena in HD. Just as in Alzheimer's, inflammation and oxidative damage play a strong role in the neurodegenerative process of HD: oxidative damage (also known as "oxidative stress") helps to degrade nerve cells in the basal ganglia and cerebral cortex; chronic inflammation in the brains of people with HD is believed to play a significant role in the progression of the disease. ( For more info about inflammation, click here.) As shown previously, curcumin was able to reduce inflammation and oxidative damage in mouse models of AD. Although it is possible that the pattern of inflammation in the brain and the severity of oxidative damage may be different between AD and HD, if they are even slightly similar in the two disorders, then one would expect curcumin to also have a positive effect on combating HD... » read the whole article |
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TIME.com » Food for the Brain |
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Fans of Indian cuisine know a spicy curry can go straight to the head�and now medical science backs them up. A recent study by researchers at the University of California Los Angeles and the Greater Los Angeles Veterans Affairs Healthcare System concludes that curcumin, the substance that gives the curry spice turmeric its yellow pigment, may help combat Alzheimer's disease. In India's ancient Ayurvedic health system, the spice is known as an anti-inflammatory and a cleanser of blood. Alzheimer's researchers became interested in it due to evidence that the prevalence of the neurological disease among the elderly in India may be considerably lower than that in the U.S... » read the whole article |
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